![]() IMPORTANT: For Plasmids, I will be purposefully leaving out any purchasable unneeded Plasmid upgrades as you don't need all Plasmid upgrades to get the highest rank in each Plasmid (e.g. For the Health/EVE Upgrades, you can decide how much of each you want from the 7 upgrades you can get with this guide. I will show you how spend your ADAM efficiently to acquire all purchasable plasmids and tonics per level whilst unlocking all gene slots and getting as many Health/EVE upgrades in the most efficient way possible by using every bit of ADAM you can obtain. ![]() This isn't a collectibles walkthrough, if you want to collect all the collectibles (Upgrades Stations, Genes, Audio Diaries etc) then click HERE (made by ShadowAFC) However if anyone wants to know how to make the most out their ADAM when harvesting all sisters then let me know and i'll add a 'Harvest-Only' guide to this thread but you will not be able to collect all Plasmids/Tonics if you do this. The guide will follow that of all 21 little sisters being rescued for the Tenenbaum Gifts (5 EXTRA GENES!) since its the only way you can acquire every Tonic/Plasmid. So I thought i'd make this guide after doing quite a bit of research and number crunching to help anyone that wants to efficiently spend their ADAM, not only for the 'Tonic Collector', but also if they don't want to waste their ADAM on Tonics/Plasmids that they don't actually need to buy.
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